Tumor necrosis factor-inducible gene 6 protein

BE0004952ProteinHumansTNFAIP6

Major regulator of extracellular matrix organization during tissue remodeling (PubMed:15917224, PubMed:18042364, PubMed:26823460). It is acted on by 3 drugs in DrugBank.

Gene name
TNFAIP6
UniProtKB entry
P98066Swiss-Prot
Cellular location
Secreted
Residues / weight
277 residues · 31,203 Da
Also known as
3.1.1.- · Hyaluronate-binding protein · TNF alpha-induced protein 6 · TNF-stimulated gene 6 protein · TSG-6

Resolves to

Protein
UniProtP98066UniProt nameTSG6_HUMAN
Gene
HGNCHGNC:11898NCBI Gene7130GeneCardsTNFAIP6
Pharmacology
KEGGhsa:7130
Structure
PDB1O7BPDB1O7CPDB2N40
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor-inducible gene 6 protein, how selective are they, and which programs against it are still in active trials?

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