Actin, cytoplasmic 2

BE0005013ProteinHumansACTG1

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. It is acted on by 2 drugs in DrugBank.

Gene name
ACTG1
UniProtKB entry
P63261Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
375 residues · 41,792 Da
Also known as
3.6.4.- · ACTG · Gamma-actin

Resolves to

Protein
UniProtP63261UniProt nameACTG_HUMAN
Gene
HGNCHGNC:144NCBI Gene71GeneCardsACTG1
Pharmacology
KEGGhsa:71
Structure
PDB5JLHPDB6CXIPDB6CXJ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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16GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Actin, cytoplasmic 2, how selective are they, and which programs against it are still in active trials?

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