Transient receptor potential cation channel subfamily V member 6

BE0005102ProteinHumansTRPV6

Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11248124, PubMed:11278579, PubMed:15184369, PubMed:23612980, PubMed:29258289). It is acted on by 4 drugs in DrugBank.

Gene name
TRPV6
UniProtKB entry
Q9H1D0Swiss-Prot
Cellular location
Cell membrane
Residues / weight
765 residues · 87,285 Da
Also known as
Calcium transport protein 1 · CaT-L · CaT-like · CaT1 · ECAC2

Resolves to

Protein
UniProtQ9H1D0UniProt nameTRPV6_HUMAN
Gene
HGNCHGNC:14006NCBI Gene55503GeneCardsTRPV6
Pharmacology
IUPHAR/GtoPdb512KEGGhsa:55503
Structure
PDB6BO8PDB6BO9PDB6BOA
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
12+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Transient receptor potential cation channel subfamily V member 6, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In