Voltage-dependent calcium channel gamma-2 subunit

BE0005108ProteinHumansCACNG2

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). It is acted on by 1 drug in DrugBank.

Gene name
CACNG2
UniProtKB entry
Q9Y698Swiss-Prot
Cellular location
Membrane
Residues / weight
323 residues · 35,965 Da
Also known as
Neuronal voltage-gated calcium channel gamma-2 subunit · TARP gamma-2 · Transmembrane AMPAR regulatory protein gamma-2

Resolves to

Protein
UniProtQ9Y698UniProt nameCCG2_HUMAN
Gene
HGNCHGNC:1406NCBI Gene10369GeneCardsCACNG2
Pharmacology
KEGGhsa:10369
Structure
PDB6DLZPDB6DM0PDB6DM1
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent calcium channel gamma-2 subunit, how selective are they, and which programs against it are still in active trials?

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