G protein-activated inward rectifier potassium channel 3

BE0005190ProteinHumansKCNJ9

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. It is acted on by 2 drugs in DrugBank.

Gene name
KCNJ9
UniProtKB entry
Q92806Swiss-Prot
Cellular location
Membrane
Residues / weight
393 residues · 44,019 Da
Also known as
GIRK-3 · GIRK3 · Inward rectifier K(+) channel Kir3.3 · Potassium channel, inwardly rectifying subfamily J member 9

Resolves to

Protein
UniProtQ92806UniProt nameKCNJ9_HUMAN
Gene
HGNCHGNC:6270NCBI Gene3765GeneCardsKCNJ9
Pharmacology
KEGGhsa:3765
Structure
PDB6X23
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on G protein-activated inward rectifier potassium channel 3, how selective are they, and which programs against it are still in active trials?

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