Solute carrier family 2, facilitated glucose transporter member 5

BE0005216ProteinHumansSLC2A5

Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). It is acted on by 4 drugs in DrugBank.

Gene name
SLC2A5
UniProtKB entry
P22732Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
501 residues · 54,973 Da
Also known as
Fructose transporter · Glucose transporter type 5, small intestine · GLUT-5 · GLUT5

Resolves to

Protein
UniProtP22732UniProt nameGTR5_HUMAN
Gene
HGNCHGNC:11010NCBI Gene6518GeneCardsSLC2A5
Pharmacology
KEGGhsa:6518
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Solute carrier family 2, facilitated glucose transporter member 5, how selective are they, and which programs against it are still in active trials?

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