CCAAT/enhancer-binding protein beta

BE0005461ProteinHumansCEBPB

Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:12048245, PubMed:1741402, PubMed:18647749, PubMed:9374525). It is acted on by 2 drugs in DrugBank.

Gene name
CEBPB
UniProtKB entry
P17676Swiss-Prot
Cellular location
Nucleus
Residues / weight
345 residues · 36,105 Da
Also known as
C/EBP beta · LAP · LIP · Liver activator protein · Liver-enriched inhibitory protein

Resolves to

Protein
UniProtP17676UniProt nameCEBPB_HUMAN
Gene
HGNCHGNC:1834NCBI Gene1051GeneCardsCEBPB
Pharmacology
KEGGhsa:1051
Structure
PDB1GTWPDB1GU4PDB1GU5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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32GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on CCAAT/enhancer-binding protein beta, and which indications are they being tested in?

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