Dihydropyrimidinase-related protein 2

BE0005806ProteinHumansDPYSL2

Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. It is acted on by 2 drugs in DrugBank.

Gene name
DPYSL2
UniProtKB entry
Q16555Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
572 residues · 62,293 Da
Also known as
Collapsin response mediator protein 2 · CRMP-2 · CRMP2 · DRP-2 · N2A3

Resolves to

Protein
UniProtQ16555UniProt nameDPYL2_HUMAN
Gene
HGNCHGNC:3014NCBI Gene1808GeneCardsDPYSL2
Pharmacology
KEGGhsa:1808
Structure
PDB2GSEPDB2VM8PDB5LXX
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2Metabolic reactionsDrug transformations it catalyses, substrate to product
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Dihydropyrimidinase-related protein 2, how selective are they, and which programs against it are still in active trials?

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