Matrix Gla protein

BE0005813ProteinHumansMGP

Associates with the organic matrix of bone and cartilage. It is acted on by 1 drug in DrugBank.

Gene name
MGP
UniProtKB entry
P08493Swiss-Prot
Cellular location
Secreted
Residues / weight
103 residues · 12,353 Da
Also known as
Cell growth-inhibiting gene 36 protein · MGLAP · MGP

Resolves to

Protein
UniProtP08493UniProt nameMGP_HUMAN
Gene
HGNCHGNC:7060NCBI Gene4256GeneCardsMGP
Pharmacology
KEGGhsa:4256
Structure
PDB9L24PDB9NUBPDB9WFC
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Matrix Gla protein, how selective are they, and which programs against it are still in active trials?

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