Copper chaperone for superoxide dismutase

BE0005815ProteinHumansCCS

Delivers copper to copper zinc superoxide dismutase (SOD1). It is acted on by 6 drugs in DrugBank.

Gene name
CCS
UniProtKB entry
O14618Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
274 residues · 29,040 Da
Also known as
Superoxide dismutase copper chaperone

Resolves to

Protein
UniProtO14618UniProt nameCCS_HUMAN
Gene
HGNCHGNC:1613NCBI Gene9973GeneCardsCCS
Pharmacology
KEGGhsa:9973
Structure
PDB1DO5PDB2CRLPDB2RSQ
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Copper chaperone for superoxide dismutase, how selective are they, and which programs against it are still in active trials?

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