Nucleolar and coiled-body phosphoprotein 1

BE0005819ProteinHumansNOLC1

Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). It is acted on by 1 drug in DrugBank.

Gene name
NOLC1
UniProtKB entry
Q14978Swiss-Prot
Cellular location
Nucleus, nucleolus
Residues / weight
699 residues · 73,602 Da
Also known as
140 kDa nucleolar phosphoprotein · HCV NS5A-transactivated protein 13 · Hepatitis C virus NS5A-transactivated protein 13 · KIAA0035 · Nopp140

Resolves to

Protein
UniProtQ14978UniProt nameNOLC1_HUMAN
Gene
HGNCHGNC:15608NCBI Gene9221GeneCardsNOLC1
Pharmacology
KEGGhsa:9221
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
23+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Nucleolar and coiled-body phosphoprotein 1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In