Apoptosis regulatory protein Siva

BE0005834ProteinHumansSIVA1

Induces CD27-mediated apoptosis. It is acted on by 4 drugs in DrugBank.

Gene name
SIVA1
UniProtKB entry
O15304Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
175 residues · 18,694 Da
Also known as
CD27-binding protein · CD27BP · SIVA

Resolves to

Protein
UniProtO15304UniProt nameSIVA_HUMAN
Gene
HGNCHGNC:17712NCBI Gene10572GeneCardsSIVA1
Pharmacology
KEGGhsa:10572
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apoptosis regulatory protein Siva, how selective are they, and which programs against it are still in active trials?

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