Utrophin

BE0005835ProteinHumansUTRN

May play a role in anchoring the cytoskeleton to the plasma membrane. It is acted on by 5 drugs in DrugBank.

Gene name
UTRN
UniProtKB entry
P46939Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
3,433 residues · 394,463 Da
Also known as
DMDL · DRP-1 · DRP1 · Dystrophin-related protein 1

Resolves to

Protein
UniProtP46939UniProt nameUTRN_HUMAN
Gene
HGNCHGNC:12635NCBI Gene7402GeneCardsUTRN
Pharmacology
KEGGhsa:7402
Structure
PDB1BHDPDB1QAGPDB6M5G
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Utrophin, how selective are they, and which programs against it are still in active trials?

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