Apolipoprotein B receptor

BE0005852ProteinHumansAPOBR

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). It is acted on by 8 drugs in DrugBank.

Gene name
APOBR
UniProtKB entry
Q0VD83Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,097 residues · 115,633 Da
Also known as
apoB-48R · APOB48R · Apolipoprotein B-100 receptor · Apolipoprotein B-48 receptor · Apolipoprotein B48 receptor

Resolves to

Protein
UniProtQ0VD83UniProt nameAPOBR_HUMAN
Gene
HGNCHGNC:24087NCBI Gene55911GeneCardsAPOBR
Pharmacology
KEGGhsa:55911
Drugs

What you can answer from here — as of September 03, 2024

8DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Apolipoprotein B receptor, how selective are they, and which programs against it are still in active trials?

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