Calcium and integrin-binding protein 1

BE0008691ProteinHumansCIB1

Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertrophy and apoptosis. It is acted on by 3 drugs in DrugBank.

Gene name
CIB1
UniProtKB entry
Q99828Swiss-Prot
Cellular location
Membrane
Residues / weight
191 residues · 21,703 Da
Also known as
Calcium- and integrin-binding protein · Calmyrin · CIB · CIBP · DNA-PKcs-interacting protein

Resolves to

Protein
UniProtQ99828UniProt nameCIB1_HUMAN
Gene
HGNCHGNC:16920NCBI Gene10519GeneCardsCIB1
Pharmacology
KEGGhsa:10519
Structure
PDB1DGUPDB1DGVPDB1XO5
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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45+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium and integrin-binding protein 1, how selective are they, and which programs against it are still in active trials?

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