Calcineurin B homologous protein 1

BE0008693ProteinHumansCHP1

Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. It is acted on by 3 drugs in DrugBank.

Gene name
CHP1
UniProtKB entry
Q99653Swiss-Prot
Cellular location
Nucleus
Residues / weight
195 residues · 22,456 Da
Also known as
Calcineurin B-like protein · Calcium-binding protein CHP · Calcium-binding protein p22 · CHP · EF-hand calcium-binding domain-containing protein p22

Resolves to

Protein
UniProtQ99653UniProt nameCHP1_HUMAN
Gene
HGNCHGNC:17433NCBI Gene11261GeneCardsCHP1
Pharmacology
KEGGhsa:11261
Structure
PDB2E30PDB7DSVPDB7DSX
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcineurin B homologous protein 1, how selective are they, and which programs against it are still in active trials?

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