Fibrillin-2

BE0008694ProteinHumansFBN2

Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. It is acted on by 3 drugs in DrugBank.

Gene name
FBN2
UniProtKB entry
P35556Swiss-Prot
Cellular location
Secreted
Residues / weight
2,912 residues · 314,772 Da

Resolves to

Protein
UniProtP35556UniProt nameFBN2_HUMAN
Gene
HGNCHGNC:3604NCBI Gene2201GeneCardsFBN2
Pharmacology
KEGGhsa:2201
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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8Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibrillin-2, how selective are they, and which programs against it are still in active trials?

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