Peflin

BE0008696ProteinHumansPEF1

Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. It is acted on by 3 drugs in DrugBank.

Gene name
PEF1
UniProtKB entry
Q9UBV8Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
284 residues · 30,381 Da
Also known as
ABP32 · PEF protein with a long N-terminal hydrophobic domain · Penta-EF hand domain-containing protein 1

Resolves to

Protein
UniProtQ9UBV8UniProt namePEF1_HUMAN
Gene
HGNCHGNC:30009NCBI Gene553115GeneCardsPEF1
Pharmacology
KEGGhsa:553115
Structure
PDB8RBH
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peflin, how selective are they, and which programs against it are still in active trials?

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