Translationally-controlled tumor protein

BE0008697ProteinHumansTPT1

Involved in calcium binding and microtubule stabilization (PubMed:12167714, PubMed:15162379, PubMed:15958728). It is acted on by 3 drugs in DrugBank.

Gene name
TPT1
UniProtKB entry
P13693Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
172 residues · 19,595 Da
Also known as
Fortilin · Histamine-releasing factor · HRF · p23 · TCTP

Resolves to

Protein
UniProtP13693UniProt nameTCTP_HUMAN
Gene
HGNCHGNC:12022NCBI Gene7178GeneCardsTPT1
Pharmacology
KEGGhsa:7178
Structure
PDB1YZ1PDB2HR9PDB3EBM
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Translationally-controlled tumor protein, how selective are they, and which programs against it are still in active trials?

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