Nucleobindin-1

BE0008700ProteinHumansNUCB1

Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis (By similarity). It is acted on by 3 drugs in DrugBank.

Gene name
NUCB1
UniProtKB entry
Q02818Swiss-Prot
Cellular location
Golgi apparatus, cis-Golgi network membrane
Residues / weight
461 residues · 53,879 Da
Also known as
CALNUC · NUC

Resolves to

Protein
UniProtQ02818UniProt nameNUCB1_HUMAN
Gene
HGNCHGNC:8043NCBI Gene4924GeneCardsNUCB1
Pharmacology
IUPHAR/GtoPdb2871KEGGhsa:4924
Structure
PDB1SNL
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Nucleobindin-1, how selective are they, and which programs against it are still in active trials?

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