Fibrillin-3

BE0008702ProteinHumansFBN3

Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. It is acted on by 3 drugs in DrugBank.

Gene name
FBN3
UniProtKB entry
Q75N90Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
2,809 residues · 300,353 Da
Also known as
KIAA1776

Resolves to

Protein
UniProtQ75N90UniProt nameFBN3_HUMAN
Gene
HGNCHGNC:18794NCBI Gene84467GeneCardsFBN3
Pharmacology
KEGGhsa:84467
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibrillin-3, how selective are they, and which programs against it are still in active trials?

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