Calreticulin-3

BE0008711ProteinHumansCALR3

During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. It is acted on by 3 drugs in DrugBank.

Gene name
CALR3
UniProtKB entry
Q96L12Swiss-Prot
Cellular location
Endoplasmic reticulum lumen
Residues / weight
384 residues · 44,995 Da
Also known as
Calreticulin-2 · Calsperin · CRT2

Resolves to

Protein
UniProtQ96L12UniProt nameCALR3_HUMAN
Gene
HGNCHGNC:20407NCBI Gene125972GeneCardsCALR3
Pharmacology
KEGGhsa:125972
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calreticulin-3, how selective are they, and which programs against it are still in active trials?

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