Splicing factor, proline- and glutamine-rich

BE0008965ProteinHumansSFPQ

DNA- and RNA binding protein, involved in several nuclear processes. It is acted on by 2 drugs in DrugBank.

Gene name
SFPQ
UniProtKB entry
P23246Swiss-Prot
Cellular location
Nucleus speckle
Residues / weight
707 residues · 76,149 Da
Also known as
100 kDa DNA-pairing protein · DNA-binding p52/p100 complex, 100 kDa subunit · hPOMp100 · Polypyrimidine tract-binding protein-associated-splicing factor · PSF

Resolves to

Protein
UniProtP23246UniProt nameSFPQ_HUMAN
Gene
HGNCHGNC:10774NCBI Gene6421GeneCardsSFPQ
Pharmacology
KEGGhsa:6421
Structure
PDB4WIIPDB4WIJPDB4WIK
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
20GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
42+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Splicing factor, proline- and glutamine-rich, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In