Prostate-specific antigen

BE0008983ProteinHumansKLK3

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. It is acted on by 7 drugs in DrugBank.

Gene name
KLK3
UniProtKB entry
P07288Swiss-Prot
Cellular location
Secreted
Residues / weight
261 residues · 28,741 Da
Also known as
3.4.21.77 · APS · Gamma-seminoprotein · Kallikrein-3 · P-30 antigen

Resolves to

Protein
UniProtP07288UniProt nameKLK3_HUMAN
Gene
HGNCHGNC:6364NCBI Gene354GeneCardsKLK3
Pharmacology
IUPHAR/GtoPdb2373KEGGhsa:354
Structure
PDB2ZCHPDB2ZCKPDB2ZCL
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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19Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Prostate-specific antigen, how selective are they, and which programs against it are still in active trials?

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