Phosphatidylinositol 4-kinase type 2-beta

BE0008985ProteinHumansPI4K2B

Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell (PubMed:11923287, PubMed:12324459). It is acted on by 1 drug in DrugBank.

Gene name
PI4K2B
UniProtKB entry
Q8TCG2Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
481 residues · 54,744 Da
Also known as
2.7.1.67 · Phosphatidylinositol 4-kinase type II-beta · PI4KII-BETA

Resolves to

Protein
UniProtQ8TCG2UniProt nameP4K2B_HUMAN
Gene
HGNCHGNC:18215NCBI Gene55300GeneCardsPI4K2B
Pharmacology
IUPHAR/GtoPdb2499KEGGhsa:55300
Structure
PDB4WTVPDB8A5XPDB9HHM
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phosphatidylinositol 4-kinase type 2-beta, and which indications are they being tested in?

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