DB02709InvestigationalSmall molecule
Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as... It exists as cis-(Z) and trans-(E) isomers.
- Mechanism
- Curator reviewed
Resveratrol suppresses NF-kappaB (NF-kappaB) activation in HSV infected cells. Reports have indicated that HSV activates NF-kappaB during productive infection and this may be an essential aspect of its replication scheme [PMID: 9705914].
- Primary indication
- Being investigated for the treatment of Herpes labialis infections (cold sores).Curator reviewed
- Formula / weight
- C14H12O3 · 228.2433 g/mol (avg)
- Also known as
- (E)-resveratrol · 3,4',5-trihydroxystilbene · 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol · 5-[(E)-2-(4-Hydroxyphenyl)-Ethenyl] Benzene-1,3 Diol · 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
- Code names
- SRT-501
Resolves to
Clinical / RWD
Structure
InChIKey
LUKBXSAWLPMMSZ-OWOJBTEDSA-NSMILESOC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1What you can answer from here — as of August 31, 2026
26Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Resveratrol, and which of those have an active Phase 3 trial?
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