Cystatin-B

BE0008992ProteinHumansCSTB

This is an intracellular thiol proteinase inhibitor. It is acted on by 1 drug in DrugBank.

Gene name
CSTB
UniProtKB entry
P04080Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
98 residues · 11,140 Da
Also known as
CPI-B · CST6 · Liver thiol proteinase inhibitor · Stefin-B · STFB

Resolves to

Protein
UniProtP04080UniProt nameCYTB_HUMAN
Gene
HGNCHGNC:2482NCBI Gene1476GeneCardsCSTB
Pharmacology
KEGGhsa:1476
Structure
PDB1STFPDB2OCTPDB4N6V
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cystatin-B, how selective are they, and which programs against it are still in active trials?

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