Neural cell adhesion molecule L1

BE0008999ProteinHumansL1CAM

Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. It is acted on by 1 drug in DrugBank.

Gene name
L1CAM
UniProtKB entry
P32004Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,257 residues · 140,002 Da
Also known as
CAML1 · MIC5 · N-CAM-L1 · NCAM-L1

Resolves to

Protein
UniProtP32004UniProt nameL1CAM_HUMAN
Gene
HGNCHGNC:6470NCBI Gene3897GeneCardsL1CAM
Pharmacology
KEGGhsa:3897
Structure
PDB8AFOPDB8AFP
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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51+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neural cell adhesion molecule L1, how selective are they, and which programs against it are still in active trials?

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