Bone morphogenetic protein 4

BE0009000ProteinHumansBMP4

Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (PubMed:31363885). It is acted on by 1 drug in DrugBank.

Gene name
BMP4
UniProtKB entry
P12644Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
408 residues · 46,555 Da
Also known as
BMP-2B · BMP-4 · BMP2B · Bone morphogenetic protein 2B · DVR4

Resolves to

Protein
UniProtP12644UniProt nameBMP4_HUMAN
Gene
HGNCHGNC:1071NCBI Gene652GeneCardsBMP4
Pharmacology
KEGGhsa:652
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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29GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Bone morphogenetic protein 4, how selective are they, and which programs against it are still in active trials?

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