Macrophage receptor MARCO

BE0009001ProteinHumansMARCO

Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). It is acted on by 2 drugs in DrugBank.

Gene name
MARCO
UniProtKB entry
Q9UEW3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
520 residues · 52,658 Da
Also known as
Macrophage receptor with collagenous structure · SCARA2 · Scavenger receptor class A member 2

Resolves to

Protein
UniProtQ9UEW3UniProt nameMARCO_HUMAN
Gene
HGNCHGNC:6895NCBI Gene8685GeneCardsMARCO
Pharmacology
KEGGhsa:8685
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Macrophage receptor MARCO, how selective are they, and which programs against it are still in active trials?

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