ATP synthase F(0) complex subunit g, mitochondrial

BE0009022ProteinHumansATP5MG

Subunit g, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron... It is acted on by 2 drugs in DrugBank.

Gene name
ATP5MG
UniProtKB entry
O75964Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
103 residues · 11,428 Da
Also known as
ATP synthase membrane subunit g · ATP5L · ATPase subunit g

Resolves to

Protein
UniProtO75964UniProt nameATP5L_HUMAN
Gene
HGNCHGNC:14247NCBI Gene10632GeneCardsATP5MG
Pharmacology
KEGGhsa:10632
Structure
PDB8H9FPDB8H9JPDB8H9M
Drugs

What you can answer from here — as of June 26, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP synthase F(0) complex subunit g, mitochondrial, how selective are they, and which programs against it are still in active trials?

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