C4b-binding protein alpha chain

BE0009050ProteinHumansC4BPA

Controls the classical pathway of complement activation. It is acted on by 5 drugs in DrugBank.

Gene name
C4BPA
UniProtKB entry
P04003Swiss-Prot
Cellular location
Secreted
Residues / weight
597 residues · 67,033 Da
Also known as
C4BP · Proline-rich protein · PRP

Resolves to

Protein
UniProtP04003UniProt nameC4BPA_HUMAN
Gene
HGNCHGNC:1325NCBI Gene722GeneCardsC4BPA
Pharmacology
KEGGhsa:722
Structure
PDB2A55PDB4B0FPDB5HYP
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on C4b-binding protein alpha chain, how selective are they, and which programs against it are still in active trials?

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