Insulin-like growth factor-binding protein complex acid labile subunit

BE0009058ProteinHumansIGFALS

Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion. It is acted on by 6 drugs in DrugBank.

Gene name
IGFALS
UniProtKB entry
P35858Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
605 residues · 66,034 Da
Also known as
ALS

Resolves to

Protein
UniProtP35858UniProt nameALS_HUMAN
Gene
HGNCHGNC:5468NCBI Gene3483GeneCardsIGFALS
Pharmacology
KEGGhsa:3483
Structure
PDB7WRQ
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Insulin-like growth factor-binding protein complex acid labile subunit, how selective are they, and which programs against it are still in active trials?

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