Inter-alpha-trypsin inhibitor heavy chain H3

BE0009081ProteinHumansITIH3

May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of... It is acted on by 4 drugs in DrugBank.

Gene name
ITIH3
UniProtKB entry
Q06033Swiss-Prot
Cellular location
Secreted
Residues / weight
890 residues · 99,849 Da
Also known as
Inter-alpha-inhibitor heavy chain 3 · ITI heavy chain H3 · ITI-HC3 · Serum-derived hyaluronan-associated protein · SHAP

Resolves to

Pharmacology

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Inter-alpha-trypsin inhibitor heavy chain H3, how selective are they, and which programs against it are still in active trials?

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