Pregnancy zone protein

BE0009089ProteinHumansPZP

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. It is acted on by 4 drugs in DrugBank.

Gene name
PZP
UniProtKB entry
P20742Swiss-Prot
Cellular location
Secreted
Residues / weight
1,482 residues · 163,862 Da
Also known as
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 · CPAMD6

Resolves to

Protein
UniProtP20742UniProt namePZP_HUMAN
Gene
HGNCHGNC:9750NCBI Gene5858GeneCardsPZP
Pharmacology
KEGGhsa:5858
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pregnancy zone protein, how selective are they, and which programs against it are still in active trials?

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