Secreted frizzled-related protein 4

BE0009094ProteinHumansSFRP4

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. It is acted on by 2 drugs in DrugBank.

Gene name
SFRP4
UniProtKB entry
Q6FHJ7Swiss-Prot
Cellular location
Secreted
Residues / weight
346 residues · 39,826 Da
Also known as
Frizzled protein, human endometrium · FRPHE · sFRP-4

Resolves to

Protein
UniProtQ6FHJ7UniProt nameSFRP4_HUMAN
Gene
HGNCHGNC:10778NCBI Gene6424GeneCardsSFRP4
Pharmacology
KEGGhsa:6424
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Secreted frizzled-related protein 4, how selective are they, and which programs against it are still in active trials?

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