Heterochromatin protein 1-binding protein 3

BE0009101ProteinHumansHP1BP3

Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). It is acted on by 1 drug in DrugBank.

Gene name
HP1BP3
UniProtKB entry
Q5SSJ5Swiss-Prot
Cellular location
Nucleus
Residues / weight
553 residues · 61,207 Da
Also known as
Protein HP1-BP74

Resolves to

Protein
UniProtQ5SSJ5UniProt nameHP1B3_HUMAN
Gene
HGNCHGNC:24973NCBI Gene50809GeneCardsHP1BP3
Pharmacology
KEGGhsa:50809
Structure
PDB2RQP
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Heterochromatin protein 1-binding protein 3, how selective are they, and which programs against it are still in active trials?

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