Histamine H1 receptor

BE0009144ProteinMouseHrh1

In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating... It is acted on by 2 drugs in DrugBank.

Gene name
Hrh1
UniProtKB entry
P70174Swiss-Prot
Cellular location
Cell membrane
Residues / weight
488 residues · 55,681 Da
Also known as
Bphs · H1R

Resolves to

Protein
UniProtP70174UniProt nameHRH1_MOUSE
Gene
NCBI Gene15465
Pharmacology
KEGGmmu:15465
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
19GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
8+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Histamine H1 receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In