Calcium-transporting ATPase

BE0009199ProteinPlasmodium falciparum (isolate K1 / Thailand)ATP6

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. It is acted on by 1 drug in DrugBank.

Gene name
ATP6
UniProtKB entry
Q08853Swiss-Prot
Cellular location
Membrane
Residues / weight
1,228 residues · 139,414 Da
Also known as
3.6.3.8 · 7.2.2.10 · Calcium pump

Resolves to

Protein
UniProtQ08853UniProt nameATC_PLAFK
Structure
PDB1U5N
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium-transporting ATPase, how selective are they, and which programs against it are still in active trials?

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