Merozoite surface protein 1

BE0009218ProteinPlasmodium falciparum (isolate CDC / Honduras)MSP1

During the asexual blood stage, involved in merozoite egress from host erythrocytes possibly via its interaction with the host cytoskeleton protein spectrin resulting in the destabilization of the host cytoskeleton and thus leading to erythrocyte... It is acted on by 1 drug in DrugBank.

Gene name
MSP1
UniProtKB entry
P13827Swiss-Prot
Cellular location
Cell membrane
Residues / weight
233 residues · 26,051 Da
Also known as
Glycoprotein 185 · GP185 · Merozoite surface antigen · Merozoite surface antigens · PMMSA

Resolves to

Protein
UniProtP13827UniProt nameMSP1_PLAFD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7Clinical trialsTrials of drugs acting on it, by phase and status
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2GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Merozoite surface protein 1, how selective are they, and which programs against it are still in active trials?

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