Adenosine deaminase

BE0009226ProteinPlasmodium falciparum (isolate 3D7)ADA

Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741, PubMed:31002765). It is acted on by 1 drug in DrugBank.

Gene name
ADA
UniProtKB entry
Q8IJA9TrEMBL
Residues / weight
367 residues · 42,466 Da
Also known as
3.5.4.4 · Adenosine deaminase, putative · S-methyl-5'-thioadenosine deaminase

Resolves to

Protein
UniProtQ8IJA9UniProt nameADA_PLAF7
Gene
NCBI Gene810446
Pharmacology
KEGGpfa:PF10_0289
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adenosine deaminase, how selective are they, and which programs against it are still in active trials?

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