Eukaryotic translation initiation factor 3 subunit C

BE0009239ProteinPlasmodium falciparum (isolate 3D7)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to... It is acted on by 1 drug in DrugBank.

UniProtKB entry
Q8I5Y3TrEMBL
Cellular location
Cytoplasm
Residues / weight
984 residues · 116,013 Da
Also known as
eIF3c · Eukaryotic translation initiation factor 3 subunit 8

Resolves to

Protein
UniProtQ8I5Y3UniProt nameQ8I5Y3_PLAF7
Gene
NCBI Gene811115
Pharmacology
KEGGpfa:PFL0310c
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Eukaryotic translation initiation factor 3 subunit C, how selective are they, and which programs against it are still in active trials?

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