Calcium-dependent protein kinase 1

BE0009379ProteinPlasmodium falciparum (isolate 3D7)CDPK1

Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:18768477, PubMed:19307175, PubMed:28680058, PubMed:29716996). It is acted on by 1 drug in DrugBank.

Gene name
CDPK1
UniProtKB entry
P62344Swiss-Prot
Cellular location
Membrane
Residues / weight
524 residues · 60,799 Da
Also known as
2.7.11.1 · CDPK1 · CPK1 · PfCDPK1

Resolves to

Protein
UniProtP62344UniProt nameCDPK1_PLAF7
Gene
NCBI Gene812762
Pharmacology
KEGGpfa:PFB0815w
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium-dependent protein kinase 1, how selective are they, and which programs against it are still in active trials?

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