Serine/threonine-protein kinase TAO1

BE0009392ProteinHumansTAOK1

Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. It is acted on by 1 drug in DrugBank.

Gene name
TAOK1
UniProtKB entry
Q7L7X3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
1,001 residues · 116,070 Da
Also known as
2.7.11.1 · hKFC-B · hTAOK1 · KIAA1361 · Kinase from chicken homolog B

Resolves to

Protein
UniProtQ7L7X3UniProt nameTAOK1_HUMAN
Gene
HGNCHGNC:29259NCBI Gene57551GeneCardsTAOK1
Pharmacology
IUPHAR/GtoPdb2233KEGGhsa:57551
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase TAO1, how selective are they, and which programs against it are still in active trials?

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