Serine/threonine-protein kinase TAO3

BE0009393ProteinHumansTAOK3

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. It is acted on by 1 drug in DrugBank.

Gene name
TAOK3
UniProtKB entry
Q9H2K8Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
898 residues · 105,405 Da
Also known as
2.7.11.1 · CTCL-associated antigen HD-CL-09 · Cutaneous T-cell lymphoma-associated antigen HD-CL-09 · Dendritic cell-derived protein kinase · DPK

Resolves to

Protein
UniProtQ9H2K8UniProt nameTAOK3_HUMAN
Gene
HGNCHGNC:18133NCBI Gene51347GeneCardsTAOK3
Pharmacology
IUPHAR/GtoPdb2235KEGGhsa:51347
Structure
PDB6BDN
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase TAO3, how selective are they, and which programs against it are still in active trials?

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