Calcium/calmodulin-dependent protein kinase kinase 1

BE0009418ProteinHumansCAMKK1

Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. It is acted on by 1 drug in DrugBank.

Gene name
CAMKK1
UniProtKB entry
Q8N5S9Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
505 residues · 55,735 Da
Also known as
2.7.11.17 · Calcium/calmodulin-dependent protein kinase kinase alpha · CaM-kinase IV kinase · CaM-kinase kinase 1 · CaM-kinase kinase alpha

Resolves to

Protein
UniProtQ8N5S9UniProt nameKKCC1_HUMAN
Gene
HGNCHGNC:1469NCBI Gene84254GeneCardsCAMKK1
Pharmacology
IUPHAR/GtoPdb1956KEGGhsa:84254
Structure
PDB6CCFPDB6CD6
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calcium/calmodulin-dependent protein kinase kinase 1, how selective are they, and which programs against it are still in active trials?

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