Calcium/calmodulin-dependent protein kinase kinase 2

BE0009419ProteinHumansCAMKK2

Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. It is acted on by 1 drug in DrugBank.

Gene name
CAMKK2
UniProtKB entry
Q96RR4Swiss-Prot
Cellular location
Nucleus
Residues / weight
588 residues · 64,745 Da
Also known as
2.7.11.17 · Calcium/calmodulin-dependent protein kinase kinase beta · CaM-kinase kinase 2 · CaM-kinase kinase beta · CaM-KK 2

Resolves to

Protein
UniProtQ96RR4UniProt nameKKCC2_HUMAN
Gene
HGNCHGNC:1470NCBI Gene10645GeneCardsCAMKK2
Pharmacology
IUPHAR/GtoPdb1957KEGGhsa:10645
Structure
PDB2ZV2PDB5UY6PDB5UYJ
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
13GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
18+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Calcium/calmodulin-dependent protein kinase kinase 2, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In