Citron Rho-interacting kinase

BE0009424ProteinHumansCIT

Plays a role in cytokinesis. It is acted on by 1 drug in DrugBank.

Gene name
CIT
UniProtKB entry
O14578Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
2,027 residues · 231,429 Da
Also known as
2.7.11.1 · CRIK · KIAA0949 · Serine/threonine-protein kinase 21 · STK21

Resolves to

Protein
UniProtO14578UniProt nameCTRO_HUMAN
Gene
HGNCHGNC:1985NCBI Gene11113GeneCardsCIT
Pharmacology
IUPHAR/GtoPdb1509KEGGhsa:11113
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Citron Rho-interacting kinase, how selective are they, and which programs against it are still in active trials?

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