Dual specificity protein kinase CLK4

BE0009426ProteinHumansCLK4

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. It is acted on by 2 drugs in DrugBank.

Gene name
CLK4
UniProtKB entry
Q9HAZ1Swiss-Prot
Cellular location
Nucleus
Residues / weight
481 residues · 57,492 Da
Also known as
2.7.12.1 · CDC-like kinase 4

Resolves to

Protein
UniProtQ9HAZ1UniProt nameCLK4_HUMAN
Gene
HGNCHGNC:13659NCBI Gene57396GeneCardsCLK4
Pharmacology
IUPHAR/GtoPdb1993KEGGhsa:57396
Structure
PDB6FYV
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Dual specificity protein kinase CLK4, how selective are they, and which programs against it are still in active trials?

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