Serine/threonine-protein kinase DCLK1

BE0009429ProteinHumansDCLK1

Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It is acted on by 1 drug in DrugBank.

Gene name
DCLK1
UniProtKB entry
O15075Swiss-Prot
Residues / weight
740 residues · 82,223 Da
Also known as
2.7.11.1 · DCAMKL1 · DCDC3A · Doublecortin domain-containing protein 3A · Doublecortin-like and CAM kinase-like 1

Resolves to

Protein
UniProtO15075UniProt nameDCLK1_HUMAN
Gene
HGNCHGNC:2700NCBI Gene9201GeneCardsDCLK1
Pharmacology
IUPHAR/GtoPdb2005KEGGhsa:9201
Structure
PDB1MFWPDB1MG4PDB1UF0
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
9GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Serine/threonine-protein kinase DCLK1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In